{"product_id":"new-product-576168","title":"TCA Rabbit Polyclonal Antibody","description":"\u003cp\u003eT cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell| the T cell receptor loci are rearranged and expressed in the order delta| gamma| beta| and alpha. If both delta and gamma rearrangements produce functional chains| the cell expresses delta and gamma. If not| the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable)| J (joining)| and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus| between the alpha V and J segments. During T cell development| the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains| the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity| resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV\/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes.\u003c\/p\u003e\n\u003cp\u003eThe TCA Rabbit Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of target proteins in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the target protein sequence, ensuring its high affinity and specificity. \u003cbr\u003e\u003cbr\u003eThe TCA Rabbit Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its superior sensitivity allows for the detection of low-abundance target proteins, making it an invaluable tool for researchers working with limited sample quantities. \u003cbr\u003e\u003cbr\u003eThis antibody is rigorously tested to ensure batch-to-batch consistency and reproducibility, guaranteeing reliable and accurate results. Its robust performance and high signal-to-noise ratio make it an ideal choice for both qualitative and quantitative protein analysis. \u003cbr\u003e\u003cbr\u003eThe TCA Rabbit Polyclonal Antibody is supplied as a liquid formulation, conveniently ready-to-use for immediate application. It is provided in a vial with optimal storage conditions, ensuring its stability and long shelf life. \u003cbr\u003e\u003cbr\u003eChoose the TCA Rabbit Polyclonal Antibody for its exceptional specificity, sensitivity, and reliability, and unlock new possibilities in your research endeavors.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47544790352152,"sku":"BT-AP12990","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_a8fa2caa-f3b1-4693-a5ce-21bb2085f499.png?v=1705666761","url":"https:\/\/danabiosci.com\/products\/new-product-576168","provider":"Dana Bioscience","version":"1.0","type":"link"}