{"product_id":"new-product-575105","title":"p53 Rabbit Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a tumor suppressor protein containing transcriptional activation| DNA binding| and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes| thereby inducing cell cycle arrest| apoptosis| senescence| DNA repair| or changes in metabolism. Mutations in this gene are associated with a variety of human cancers| including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546| 20937277).\u003c\/p\u003e\n\u003cp\u003eThe P53 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of the P53 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human P53 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the P53 protein, making it an ideal tool for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe P53 Rabbit Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a P53 protein column. This ensures that the antibody is highly specific and free from any non-specific binding. The antibody is also validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence, ensuring that it is suitable for a wide range of research applications.\u003cbr\u003e\u003cbr\u003eOverall, the P53 Rabbit Polyclonal Antibody is a highly reliable and sensitive immunological reagent that is ideal for the detection and quantification of P53 protein in various biological samples. Its high specificity and sensitivity make it an essential tool for researchers studying the role of P53 in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47544258035992,"sku":"BT-AP11724","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_abc9c06f-0b75-435d-8df9-39e7ad96ba5e.png?v=1705661257","url":"https:\/\/danabiosci.com\/products\/new-product-575105","provider":"Dana Bioscience","version":"1.0","type":"link"}