{"product_id":"new-product-574495","title":"LATS1\/2(Phospho-Ser909) Rabbit Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a putative serine\/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner| with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity| indicating a role as a negative regulator of CDC2\/cyclin A. In addition| the C-terminal kinase domain binds to its own N-terminal region| suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen\u003c\/p\u003e\n\u003cp\u003eIntroducing the LATS1\/2(Phospho-Ser909) Rabbit Polyclonal Antibody, a highly specialized and meticulously developed product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody, derived from rabbits, exhibits exceptional specificity and sensitivity in detecting and quantifying the phosphorylation of Serine 909 on the LATS1\/2 protein.\u003cbr\u003e\u003cbr\u003eWith its advanced formulation, this antibody offers unparalleled accuracy and reliability, ensuring precise and reproducible results in various experimental applications. Its polyclonal nature allows for enhanced binding affinity, enabling the detection of even low abundance targets with utmost efficiency.\u003cbr\u003e\u003cbr\u003eThe LATS1\/2(Phospho-Ser909) Rabbit Polyclonal Antibody has undergone rigorous quality control measures to guarantee optimal performance. Its purity and potency have been thoroughly assessed, ensuring minimal cross-reactivity and maximum specificity towards the target epitope. This antibody exhibits minimal background noise, facilitating clear and unambiguous interpretation of experimental data.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody has been validated for use in various techniques, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for seamless integration into diverse experimental workflows, providing researchers with the flexibility they require to explore the intricacies of LATS1\/2 phosphorylation.\u003cbr\u003e\u003cbr\u003eIn summary, the LATS1\/2(Phospho-Ser909) Rabbit Polyclonal Antibody represents a cutting-edge tool for the investigation of LATS1\/2 protein phosphorylation. Its exceptional specificity, sensitivity, and versatility make it an indispensable asset for researchers seeking to unravel the complexities of molecular biology. Trust in this antibody to deliver accurate and reproducible results, propelling scientific advancements in the field.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47544075845912,"sku":"BT-AP03378","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_41c33fd4-f6e5-472b-9a29-f8cd53618efa.png?v=1705658059","url":"https:\/\/danabiosci.com\/products\/new-product-574495","provider":"Dana Bioscience","version":"1.0","type":"link"}