{"product_id":"new-product-574135","title":"HMGN1\/2\/3\/4 (Acetyl Lys27\/K33\/K31) Rabbit Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein| HMG17| the encoded protein may help maintain an open chromatin configuration around transcribable genes.\u003c\/p\u003e\n\u003cp\u003eThe HMGN1\/2\/3\/4 (Acetyl Lys27\/K33\/K31) Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of HMGN1\/2\/3\/4 proteins in various biological samples. This antibody is produced by immunizing rabbits with synthetic peptides corresponding to the acetylated lysine residues at positions 27, 33, and 31 of the HMGN1\/2\/3\/4 proteins. The resulting polyclonal antibody exhibits high affinity and specificity towards the acetylated forms of HMGN1\/2\/3\/4, making it an ideal tool for studying the role of these proteins in chromatin structure and gene expression regulation.\u003cbr\u003e\u003cbr\u003eThe HMGN1\/2\/3\/4 (Acetyl Lys27\/K33\/K31) Rabbit Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunoprecipitation, and immunofluorescence microscopy. It has been shown to detect endogenous levels of acetylated HMGN1\/2\/3\/4 proteins in various cell lines and tissues, and can be used to monitor changes in their expression levels under different experimental conditions.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a purified IgG fraction, and has been affinity-purified using immobilized acetylated peptides to ensure maximum specificity and minimal cross-reactivity with non-acetylated forms of HMGN1\/2\/3\/4. It is provided in a convenient 100 µg size, and is suitable for use in both basic research and clinical applications.\u003cbr\u003e\u003cbr\u003eOverall, the HMGN1\/2\/3\/4 (Acetyl Lys27\/K33\/K31) Rabbit Polyclonal Antibody is a reliable and high-quality reagent that can be used to study the function and regulation of HMGN1\/2\/3\/4 proteins in various biological systems. Its high specificity and sensitivity make it an essential tool for researchers working in the fields of chromatin biology, gene expression regulation, and epigenetics.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543987175704,"sku":"BT-AP10458","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_837b9ffc-7c69-4d3d-81bd-f1e5b967acee.png?v=1705656231","url":"https:\/\/danabiosci.com\/products\/new-product-574135","provider":"Dana Bioscience","version":"1.0","type":"link"}