{"product_id":"new-product-574127","title":"HMG-1 (Acetyl Lys3) Rabbit Polyclonal Antibody","description":"\u003cp\u003eBinds preferentially single-stranded DNA and unwinds double stranded DNA.|Belongs to the HMGB family.|Contains 2 HMG box DNA-binding domains.|\u003c\/p\u003e\n\u003cp\u003eThe HMG-1 (Acetyl Lys3) Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of HMG-1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the acetylated lysine 3 residue of HMG-1 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the acetylated form of HMG-1 protein, making it an ideal tool for studying the role of HMG-1 in various cellular processes.\u003cbr\u003e\u003cbr\u003eThe HMG-1 protein is a highly conserved nuclear protein that plays a critical role in DNA binding and transcriptional regulation. The acetylation of lysine 3 residue in HMG-1 has been shown to modulate its DNA binding activity and transcriptional activity. Therefore, the HMG-1 (Acetyl Lys3) Rabbit Polyclonal Antibody can be used to study the functional significance of HMG-1 acetylation in various biological processes.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been shown to detect endogenous levels of acetylated HMG-1 protein in various cell lines and tissues. The HMG-1 (Acetyl Lys3) Rabbit Polyclonal Antibody is supplied as a purified IgG fraction, which can be used at a recommended dilution of 1:1000 for Western blotting and 1:200 for immunofluorescence.\u003cbr\u003e\u003cbr\u003eIn summary, the HMG-1 (Acetyl Lys3) Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent that can be used to study the functional significance of HMG-1 acetylation in various biological processes. Its high affinity and specificity towards the acetylated form of HMG-1 protein make it an ideal tool for researchers studying the role of HMG-1 in DNA binding and transcriptional regulation.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543983735064,"sku":"BT-AP03010","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e5445582-d76e-4f7b-be5a-0492a0e1c66a.png?v=1705656176","url":"https:\/\/danabiosci.com\/products\/new-product-574127","provider":"Dana Bioscience","version":"1.0","type":"link"}