{"product_id":"new-product-574097","title":"Histone H2A (Acetyl Lys119) Rabbit Polyclonal Antibody","description":"\u003cp\u003eHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes.\u003c\/p\u003e\n\u003cp\u003eThe linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\u003cp\u003eThe Histone H2A (Acetyl Lys119) Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Histone H2A protein acetylated at Lysine 119. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eHistone H2A is a crucial component of nucleosomes, which are the basic units of chromatin structure. Acetylation of Lysine 119 on Histone H2A has been implicated in various biological processes, including gene expression regulation, DNA repair, and chromatin remodeling. Therefore, the ability to accurately detect and quantify Histone H2A acetylated at Lysine 119 is of utmost importance in understanding the intricate mechanisms underlying these processes.\u003cbr\u003e\u003cbr\u003eThis rabbit polyclonal antibody has been extensively validated and optimized to ensure exceptional performance and reproducibility. It exhibits high affinity and specificity towards Histone H2A acetylated at Lysine 119, enabling precise and reliable detection even in low abundance samples. Additionally, this antibody demonstrates minimal cross-reactivity with other histone modifications or non-acetylated forms of Histone H2A, further enhancing its specificity.\u003cbr\u003e\u003cbr\u003eThe Histone H2A (Acetyl Lys119) Rabbit Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. Its robust formulation ensures long-term stability and consistent performance, allowing for reliable and reproducible results across multiple experiments.\u003cbr\u003e\u003cbr\u003eIn summary, the Histone H2A (Acetyl Lys119) Rabbit Polyclonal Antibody is an indispensable tool for researchers studying histone modifications and their role in various biological processes. With its exceptional sensitivity, specificity, and ease of use, this antibody enables accurate detection and quantification of Histone H2A acetylated at Lysine 119, facilitating a deeper understanding of chromatin dynamics and gene regulation.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543971119384,"sku":"BT-AP10403","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_cc365c6b-b55d-4202-a29e-197597d2bdc6.png?v=1705656037","url":"https:\/\/danabiosci.com\/products\/new-product-574097","provider":"Dana Bioscience","version":"1.0","type":"link"}