{"product_id":"new-product-574026","title":"GSTM3 Rabbit Polyclonal Antibody","description":"\u003cp\u003eCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present| eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha| kappa| mu| omega| pi| sigma| theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds| including carcinogens| therapeutic drugs| environmental toxins and products of oxidative stress| by conjugation with glutathione.\u003c\/p\u003e\n\u003cp\u003eThe genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers| likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe GSTM3 Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Glutathione S-transferase Mu 3 (GSTM3) protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, ensuring its exceptional affinity and selectivity towards GSTM3.\u003cbr\u003e\u003cbr\u003eWith its superior performance, this antibody offers researchers a reliable and accurate means to investigate the expression and localization of GSTM3 in diverse experimental settings. It is particularly valuable in studies related to drug metabolism, carcinogenesis, and oxidative stress, where GSTM3 plays a crucial role.\u003cbr\u003e\u003cbr\u003eThe GSTM3 Rabbit Polyclonal Antibody exhibits exceptional sensitivity, enabling the detection of even low levels of GSTM3 protein. Its robust specificity ensures minimal cross-reactivity with other related proteins, guaranteeing precise and reliable results. This antibody has been extensively validated in various applications, including Western blotting, immunohistochemistry, and immunofluorescence, demonstrating its versatility and suitability for a wide range of experimental techniques.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody has been rigorously quality-controlled to ensure consistent and reproducible results. It is manufactured under strict manufacturing processes and undergoes thorough testing to meet the highest standards of performance and reliability. Each batch is accompanied by a detailed datasheet, providing comprehensive information on its recommended usage, storage conditions, and handling instructions.\u003cbr\u003e\u003cbr\u003eIn summary, the GSTM3 Rabbit Polyclonal Antibody is an indispensable tool for researchers seeking to explore the intricate functions and mechanisms of GSTM3 protein. Its exceptional sensitivity, specificity, and reliability make it an ideal choice for a wide range of applications, facilitating groundbreaking discoveries in the fields of drug development, cancer research, and oxidative stress studies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543948607768,"sku":"BT-AP10306","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_6adacfa5-c14c-43be-b289-06d9b7405146.png?v=1705655648","url":"https:\/\/danabiosci.com\/products\/new-product-574026","provider":"Dana Bioscience","version":"1.0","type":"link"}