{"product_id":"new-product-573509","title":"eIF2B(Phospho Ser67) Rabbit Polyclonal Antibody","description":"\u003cp\u003eEukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits| alpha| beta| and gamma| with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP| which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe eIF2B(Phospho Ser67) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of eIF2B protein phosphorylated at Ser67. This antibody has been meticulously developed using advanced immunization techniques and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe eIF2B protein plays a crucial role in the regulation of protein synthesis initiation, and its phosphorylation at Ser67 has been implicated in various cellular processes, such as stress response and cell cycle control. This antibody specifically recognizes the phosphorylated form of eIF2B at Ser67, enabling researchers to investigate the dynamic phosphorylation status of this protein and its functional implications.\u003cbr\u003e\u003cbr\u003eThe eIF2B(Phospho Ser67) Rabbit Polyclonal Antibody exhibits exceptional sensitivity and specificity, allowing for accurate and reliable detection of phosphorylated eIF2B in complex biological samples. Its high affinity for the target epitope ensures minimal cross-reactivity with non-phosphorylated eIF2B or other proteins, thereby enhancing the accuracy of experimental results.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated using a variety of experimental approaches, including peptide blocking, knockdown\/knockout studies, and positive control experiments. It has demonstrated excellent performance in detecting phosphorylated eIF2B in various cell lines and tissues, making it an invaluable tool for researchers studying the role of eIF2B phosphorylation in cellular processes and disease pathogenesis.\u003cbr\u003e\u003cbr\u003eThe eIF2B(Phospho Ser67) Rabbit Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. It is provided in a convenient format, ensuring ease of use and compatibility with standard laboratory protocols. Each batch of antibody undergoes rigorous quality control procedures to guarantee consistent performance and reproducibility.\u003cbr\u003e\u003cbr\u003eIn summary, the eIF2B(Phospho Ser67) Rabbit Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of phosphorylated eIF2B at Ser67. Its exceptional sensitivity, specificity, and validated performance make it an indispensable asset for researchers investigating the functional significance of eIF2B phosphorylation in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543730798872,"sku":"BT-AP09540","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4afa31cd-5572-42bc-ad98-4b7452333b85.png?v=1705652872","url":"https:\/\/danabiosci.com\/products\/new-product-573509","provider":"Dana Bioscience","version":"1.0","type":"link"}