{"product_id":"new-product-573444","title":"DUOX1 Rabbit Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter| thyroperoxidase| and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase| lactoperoxidase| and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.\u003c\/p\u003e\n\u003cp\u003eThe DUOX1 Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of DUOX1 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and specificity towards DUOX1. \u003cbr\u003e\u003cbr\u003eDUOX1, also known as Dual oxidase 1, is a member of the NADPH oxidase family and plays a crucial role in the production of reactive oxygen species (ROS) in the thyroid gland. It is primarily expressed in the thyroid follicular cells and is involved in the synthesis of thyroid hormones. Dysregulation of DUOX1 expression has been implicated in various thyroid disorders, including goiter and thyroid cancer.\u003cbr\u003e\u003cbr\u003eThe DUOX1 Rabbit Polyclonal Antibody offers exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results. \u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It has been rigorously tested for quality and consistency, guaranteeing reproducible results with every experiment. The DUOX1 Rabbit Polyclonal Antibody is available in various sizes to accommodate different experimental needs.\u003cbr\u003e\u003cbr\u003eIn summary, the DUOX1 Rabbit Polyclonal Antibody is a valuable tool for researchers studying DUOX1 protein expression and its role in thyroid physiology and pathology. Its high specificity, sensitivity, and reliability make it an indispensable asset in the field of molecular biology and biomedical research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543723000088,"sku":"BT-AP02326","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_4a872a49-df86-4502-8f31-38d7b26bacbc.png?v=1705652529","url":"https:\/\/danabiosci.com\/products\/new-product-573444","provider":"Dana Bioscience","version":"1.0","type":"link"}