{"product_id":"new-product-573411","title":"DOXA1 Rabbit Polyclonal Antibody","description":"\u003cp\u003eDual oxidases DUOX1 and DUOX2 are NADPH oxidases which are involved in hydrogen peroxide production necessary for thyroid hormonogenesis. They form a heterodimer with specific maturation factors DUOXA1 and DUOXA2| respectively| which is essential for the maturation and function of the DUOX enzyme complexes. This gene encodes the DUOX1 activator or maturation factor DUOXA1. Rat studies identified a bidirectional promoter which controls the transcription of the DUOX1 and DUOXA1 genes. This protein is cotransported to the cell surface when coexpressed with DUOX1 and is retained in the endoplasmic reticulum when expressed without DUOX1 protein. The expression of this gene or the DUOX1 gene is not suppressed by thyroglobulin (Tg)| a macromolecular precursor in thyroid hormone synthesis| while the expression of the DUOX2 and DUOXA2 are significantly suppressed by the Tg. This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe DOXA1 Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of DOXA1 protein in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and accuracy in experimental settings.\u003cbr\u003e\u003cbr\u003eThe DOXA1 Rabbit Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling precise and reproducible results. It has been extensively tested in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence, demonstrating its versatility and robustness.\u003cbr\u003e\u003cbr\u003eThis antibody is produced using high-quality rabbit polyclonal antibodies, ensuring a consistent and reliable supply. It has been purified using advanced techniques to remove any non-specific binding, resulting in a highly pure and specific antibody preparation.\u003cbr\u003e\u003cbr\u003eThe DOXA1 Rabbit Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, ready-to-use for immediate application in your experiments. Each vial contains a sufficient amount of antibody for multiple experiments, ensuring cost-effectiveness and minimizing wastage.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the DOXA1 Rabbit Polyclonal Antibody is an indispensable tool for researchers studying DOXA1 protein and its role in various biological processes. Whether you are investigating DOXA1 expression patterns, protein-protein interactions, or functional studies, this antibody will provide accurate and reproducible results, facilitating your research and advancing scientific knowledge.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543674405144,"sku":"BT-AP02293","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_7abee057-bc9e-4b1c-80b1-4426a8ec869a.png?v=1705650857","url":"https:\/\/danabiosci.com\/products\/new-product-573411","provider":"Dana Bioscience","version":"1.0","type":"link"}