{"product_id":"new-product-573410","title":"Doublecortin(Phospho-Ser297) Rabbit Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains| which bind microtubules. In the developing cortex| cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition| the encoded protein interacts with LIS1| the regulatory gamma subunit of platelet activating factor acetylhydrolase| and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex| leading to epilepsy| mental retardation| subcortical band heterotopia (\"double cortex\" syndrome) in females and lissencephaly (\"smooth brain\u0026amp;quo\u003c\/p\u003e\n\u003cp\u003eThe Doublecortin(Phospho-Ser297) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Doublecortin protein phosphorylated at Serine 297. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional sensitivity and specificity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Doublecortin(Phospho-Ser297) Rabbit Polyclonal Antibody is produced using high-quality rabbit polyclonal antibodies that have been affinity-purified to ensure maximum specificity and minimal cross-reactivity. This rigorous purification process guarantees consistent and reproducible results, making it an ideal choice for researchers and scientists working in the field of neuroscience and neurodevelopment.\u003cbr\u003e\u003cbr\u003eWith its superior performance, this antibody enables precise and accurate detection of Doublecortin protein phosphorylated at Serine 297, a crucial post-translational modification associated with neuronal migration and differentiation. Its exceptional sensitivity allows for the detection of low-abundance targets, while its high specificity ensures minimal background noise, resulting in clear and reliable data interpretation.\u003cbr\u003e\u003cbr\u003eThe Doublecortin(Phospho-Ser297) Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming and complex antibody preparation procedures. Its long shelf life and stability ensure consistent performance over an extended period, providing researchers with reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eIn summary, the Doublecortin(Phospho-Ser297) Rabbit Polyclonal Antibody is a valuable tool for the investigation of Doublecortin protein phosphorylation at Serine 297. Its exceptional sensitivity, specificity, and ease of use make it an indispensable asset for researchers seeking to unravel the intricate mechanisms underlying neurodevelopment and neuronal migration.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543674044696,"sku":"BT-AP09322","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_af180c14-4484-48b1-8123-2e14c22062b6.png?v=1705650850","url":"https:\/\/danabiosci.com\/products\/new-product-573410","provider":"Dana Bioscience","version":"1.0","type":"link"}