{"product_id":"new-product-573283","title":"IKK alpha\/beta(Phospho Ser176\/177) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the serine\/threonine protein kinase family. The encoded protein| a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex| phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway| thereby activating the transcription factor.\u003c\/p\u003e\n\u003cp\u003eThe IKK alpha\/beta(Phospho Ser176\/177) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of IKK alpha and beta proteins phosphorylated at Ser176 and Ser177 residues. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target proteins.\u003cbr\u003e\u003cbr\u003eIKK alpha and beta are key components of the IKK complex, which plays a crucial role in the regulation of NF-κB signaling pathway. Phosphorylation of IKK alpha and beta at Ser176 and Ser177 residues is known to be essential for their activation and subsequent downstream signaling events. Therefore, the detection and quantification of phosphorylated IKK alpha and beta proteins are of great importance in understanding the molecular mechanisms underlying NF-κB signaling.\u003cbr\u003e\u003cbr\u003eThe IKK alpha\/beta(Phospho Ser176\/177) Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results. This antibody is suitable for use in both research and clinical settings, enabling scientists and clinicians to gain valuable insights into the role of IKK alpha and beta phosphorylation in various physiological and pathological processes.\u003cbr\u003e\u003cbr\u003eWith its superior quality and performance, the IKK alpha\/beta(Phospho Ser176\/177) Polyclonal Antibody is an indispensable tool for researchers and clinicians working in the fields of molecular biology, immunology, and signal transduction. Its ability to accurately detect and quantify phosphorylated IKK alpha and beta proteins makes it an invaluable asset in advancing our understanding of NF-κB signaling and its implications in various diseases, including cancer, inflammation, and autoimmune disorders.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543634886936,"sku":"BT-AP09005","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_cc89fcf9-120d-4016-9918-48752e39f298.png?v=1705650208","url":"https:\/\/danabiosci.com\/products\/new-product-573283","provider":"Dana Bioscience","version":"1.0","type":"link"}