{"product_id":"new-product-573239","title":"IGF2R(Phospho-Ser2484) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions| including in the intracellular trafficking of lysosomal enzymes| the activation of transforming growth factor beta| and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however| imprinting of the human gene may be polymorphic| as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611).\u003c\/p\u003e\n\u003cp\u003eThe IGF2R(Phospho-Ser2484) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IGF2R protein phosphorylated at Ser2484. This antibody is produced using advanced techniques in polyclonal antibody development, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eThe IGF2R protein plays a crucial role in regulating cellular processes such as growth, development, and metabolism. Phosphorylation of the IGF2R protein at Ser2484 has been implicated in various cellular signaling pathways, making it an important target for research in the field of molecular biology and biochemistry.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of the phosphorylated IGF2R protein in various biological samples.\u003cbr\u003e\u003cbr\u003eThe IGF2R(Phospho-Ser2484) Polyclonal Antibody is manufactured using high-quality materials and undergoes stringent quality control measures to ensure consistent and reproducible results. It is supplied as a liquid formulation, ready for immediate use, and is compatible with a wide range of experimental conditions.\u003cbr\u003e\u003cbr\u003eResearchers and scientists can rely on the IGF2R(Phospho-Ser2484) Polyclonal Antibody to facilitate their investigations into the role and function of phosphorylated IGF2R protein in cellular processes. Its exceptional performance and reliability make it an indispensable tool for studying molecular mechanisms and signaling pathways associated with IGF2R phosphorylation.\u003cbr\u003e\u003cbr\u003eNote: This product is for research use only and is not intended for diagnostic or therapeutic purposes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543617519896,"sku":"BT-AP08854","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_d6f0001d-d7cd-4fa6-883f-c44c9a624517.png?v=1705650009","url":"https:\/\/danabiosci.com\/products\/new-product-573239","provider":"Dana Bioscience","version":"1.0","type":"link"}