{"product_id":"new-product-573041","title":"ZAP-70(Phospho Tyr315) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes an enzyme belonging to the protein tyrosine kinase family| and it plays a role in T-cell development and lymphocyte activation. This enzyme| which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation| functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases| Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect| a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe ZAP-70(Phospho Tyr315) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of ZAP-70 phosphorylated at Tyr315. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target antigen.\u003cbr\u003e\u003cbr\u003eZAP-70, also known as zeta-chain-associated protein kinase 70, plays a crucial role in T-cell receptor signaling and activation. Phosphorylation of ZAP-70 at Tyr315 is a key event in the activation of T-cells and is associated with various immune disorders and diseases.\u003cbr\u003e\u003cbr\u003eThe ZAP-70(Phospho Tyr315) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of ZAP-70 phosphorylated at Tyr315 in various sample types.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and quantity, ensuring cost-effectiveness and minimizing waste. The product is manufactured under strict quality control standards, guaranteeing consistent and reproducible results.\u003cbr\u003e\u003cbr\u003eIn summary, the ZAP-70(Phospho Tyr315) Polyclonal Antibody is a valuable tool for researchers and clinicians studying T-cell signaling and associated diseases. Its high specificity, sensitivity, and versatility make it an essential component in the investigation of ZAP-70 phosphorylation and its implications in various pathological conditions.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543532290328,"sku":"BT-AP01826","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_457dec70-0377-4d7e-b146-f9077001a778.png?v=1705649025","url":"https:\/\/danabiosci.com\/products\/new-product-573041","provider":"Dana Bioscience","version":"1.0","type":"link"}