{"product_id":"new-product-573012","title":"Collagen XVIII alpha 1(Cleaved-His1572) Rabbit Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins| extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin| a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities| so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eIntroducing the Collagen XVIII alpha 1(Cleaved-His1572) Rabbit Polyclonal Antibody, a highly specific and sensitive tool for the detection of Collagen XVIII alpha 1 protein in various biological samples. This antibody has been raised in rabbits using a synthetic peptide corresponding to the cleaved His1572 region of Collagen XVIII alpha 1 protein as an immunogen. The antibody has been purified using protein A affinity chromatography and characterized for its specificity and sensitivity by various immunoassays.\u003cbr\u003e\u003cbr\u003eThe Collagen XVIII alpha 1(Cleaved-His1572) Rabbit Polyclonal Antibody is suitable for use in various applications such as Western blotting, immunohistochemistry, and ELISA. It recognizes the cleaved His1572 region of Collagen XVIII alpha 1 protein with high specificity and sensitivity, making it an ideal tool for the detection and quantification of Collagen XVIII alpha 1 protein in biological samples.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different applications. The Collagen XVIII alpha 1(Cleaved-His1572) Rabbit Polyclonal Antibody is a reliable and high-quality product that is backed by our commitment to quality and customer satisfaction.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543521870104,"sku":"BT-AP08259","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_5cd19bea-4914-4cf3-83a7-b3582d523c56.png?v=1705648887","url":"https:\/\/danabiosci.com\/products\/new-product-573012","provider":"Dana Bioscience","version":"1.0","type":"link"}