{"product_id":"new-product-573001","title":"Troponin I-C(Phospho Ser22\/S23) Polyclonal Antibody","description":"\u003cp\u003eTroponin I (TnI)| along with troponin T (TnT) and troponin C (TnC)| is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch| TnI-skeletal-slow-twitch| and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).\u003c\/p\u003e\n\u003cp\u003eThe Troponin I-C(Phospho Ser22\/S23) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Troponin I-C protein phosphorylated at Serine 22 and Serine 23 residues. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eTroponin I-C is an essential component of the troponin complex, which plays a crucial role in regulating muscle contraction. Phosphorylation of Troponin I-C at Serine 22 and Serine 23 residues has been implicated in various physiological and pathological processes, including cardiac muscle development, cardiac hypertrophy, and heart failure.\u003cbr\u003e\u003cbr\u003eThe Troponin I-C(Phospho Ser22\/S23) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated Troponin I-C and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use in various applications, including research studies, diagnostic assays, and drug development. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and biological fluids.\u003cbr\u003e\u003cbr\u003eWith its exceptional performance and reliability, the Troponin I-C(Phospho Ser22\/S23) Polyclonal Antibody is an indispensable tool for researchers and clinicians working in the field of cardiovascular biology and pathology. Its high specificity and sensitivity make it an ideal choice for investigating the role of Troponin I-C phosphorylation in various physiological and pathological conditions.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543515840792,"sku":"BT-AP08237","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_25f2581b-49a8-4bb6-9935-e315c35840e2.png?v=1705648822","url":"https:\/\/danabiosci.com\/products\/new-product-573001","provider":"Dana Bioscience","version":"1.0","type":"link"}