{"product_id":"new-product-572987","title":"Topo II alpha(Phospho Ser1525) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a DNA topoisomerase| an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation| chromatid separation| and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another| thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form| alpha| is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also pla\u003c\/p\u003e\n\u003cp\u003eThe Topo II alpha(Phospho Ser1525) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Topoisomerase II alpha protein phosphorylated at Ser1525. This antibody has been meticulously developed and validated to ensure optimal performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Topo II alpha(Phospho Ser1525) Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise detection of the phosphorylated form of Topoisomerase II alpha. It has been rigorously tested against a wide range of samples, ensuring consistent and reproducible results.\u003cbr\u003e\u003cbr\u003eThis antibody is produced using high-quality materials and state-of-the-art techniques, guaranteeing superior performance and reliability. It has been extensively characterized to ensure batch-to-batch consistency, providing researchers with a reliable and consistent tool for their experiments.\u003cbr\u003e\u003cbr\u003eThe Topo II alpha(Phospho Ser1525) Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. It is provided in a liquid form, eliminating the need for reconstitution, and is compatible with a variety of commonly used buffers and diluents.\u003cbr\u003e\u003cbr\u003eWith its exceptional specificity, sensitivity, and reliability, the Topo II alpha(Phospho Ser1525) Polyclonal Antibody is an indispensable tool for researchers studying the phosphorylation of Topoisomerase II alpha. Its versatility and robust performance make it an ideal choice for a wide range of applications in molecular biology and biomedical research.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543506731288,"sku":"BT-AP01745","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_6656d277-e477-4efa-9970-1d813b7f91cf.png?v=1705648750","url":"https:\/\/danabiosci.com\/products\/new-product-572987","provider":"Dana Bioscience","version":"1.0","type":"link"}