{"product_id":"new-product-572876","title":"SIRT1(Phospho Ser47) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the sirtuin family of proteins| homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however| yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe SIRT1(Phospho Ser47) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of SIRT1 protein phosphorylated at Serine 47. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eSIRT1, also known as NAD-dependent deacetylase sirtuin-1, is a key regulator of cellular processes such as aging, metabolism, and stress response. Phosphorylation of SIRT1 at Serine 47 has been implicated in the modulation of its enzymatic activity and protein stability, making it a crucial site for investigation.\u003cbr\u003e\u003cbr\u003eThe SIRT1(Phospho Ser47) Polyclonal Antibody exhibits exceptional specificity towards the phosphorylated form of SIRT1, enabling accurate and precise detection in various experimental settings. It has been extensively validated for use in Western blotting, immunohistochemistry, and immunofluorescence applications.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The SIRT1(Phospho Ser47) Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.\u003cbr\u003e\u003cbr\u003eWith its superior sensitivity and specificity, the SIRT1(Phospho Ser47) Polyclonal Antibody is an indispensable tool for researchers studying the role of SIRT1 phosphorylation in various biological processes. Its reliable performance and consistent results make it an ideal choice for both basic research and drug development studies.\u003cbr\u003e\u003cbr\u003eOrder your SIRT1(Phospho Ser47) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of SIRT1 regulation.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543463739672,"sku":"BT-AP07980","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_41400dab-d692-469e-9f05-d7efb5d1f3a1.png?v=1705648208","url":"https:\/\/danabiosci.com\/products\/new-product-572876","provider":"Dana Bioscience","version":"1.0","type":"link"}