{"product_id":"new-product-572818","title":"CI072 Rabbit Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene plays an important role in the regulation of endosomal trafficking| and has been shown to interact with Rab proteins that are involved in autophagy and endocytic transport. Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778| 21944779). Studies suggest that hexanucleotide expansions could result in the selective stabilization of repeat-containing pre-mRNA| and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093). Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\u003cp\u003eThe CI072 Rabbit Polyclonal Antibody is a highly specific and reliable tool for various research applications. This antibody is produced using high-quality rabbit immunoglobulins, ensuring exceptional sensitivity and specificity. It has been extensively validated for use in immunohistochemistry, immunofluorescence, and Western blotting techniques.\u003cbr\u003e\u003cbr\u003eThe CI072 Rabbit Polyclonal Antibody exhibits excellent performance in detecting and quantifying target proteins in a wide range of samples, including tissue sections, cell lysates, and whole-cell extracts. Its superior affinity and selectivity enable accurate and reproducible results, making it an ideal choice for both qualitative and quantitative analyses.\u003cbr\u003e\u003cbr\u003eThis antibody is designed to target a specific antigen, offering researchers the ability to investigate the expression and localization of their protein of interest with utmost precision. Its robust performance and low background staining ensure reliable and interpretable data, facilitating meaningful conclusions and advancing scientific discoveries.\u003cbr\u003e\u003cbr\u003eThe CI072 Rabbit Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for immediate application in various experimental settings. It is provided in a liquid formulation, ensuring ease of use and minimizing the risk of sample contamination. Each vial is quality-controlled to meet the highest standards, guaranteeing consistent and reproducible results.\u003cbr\u003e\u003cbr\u003eIn summary, the CI072 Rabbit Polyclonal Antibody is a superior research tool that offers exceptional sensitivity, specificity, and reliability. Its outstanding performance in various applications makes it an invaluable asset for scientists and researchers in the field.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543452959000,"sku":"BT-AP07797","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_46c9f36f-05e4-4e12-bcb3-19aeb242cc5a.png?v=1705647888","url":"https:\/\/danabiosci.com\/products\/new-product-572818","provider":"Dana Bioscience","version":"1.0","type":"link"}