{"product_id":"new-product-572791","title":"PYK2(Phospho Tyr881) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration| nicotinic acetylcholine receptor activation| membrane depolarization| or protein kinase C activation. This protein has been shown to bind CRK-associated substrate| nephrocystin| GTPase regulator associated with FAK| and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity t\u003c\/p\u003e\n\u003cp\u003eThe PYK2(Phospho Tyr881) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PYK2 protein phosphorylated at tyrosine 881. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.\u003cbr\u003e\u003cbr\u003ePYK2, also known as protein tyrosine kinase 2 beta, is a non-receptor tyrosine kinase that plays a crucial role in various cellular processes, including cell adhesion, migration, and proliferation. Phosphorylation of PYK2 at tyrosine 881 is a key event in the activation of this protein and subsequent downstream signaling pathways.\u003cbr\u003e\u003cbr\u003eThe PYK2(Phospho Tyr881) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The PYK2(Phospho Tyr881) Polyclonal Antibody is suitable for use in both research and clinical applications, enabling the investigation of PYK2 phosphorylation in various biological samples.\u003cbr\u003e\u003cbr\u003eIn summary, the PYK2(Phospho Tyr881) Polyclonal Antibody is a highly specific and sensitive tool that enables the detection and quantification of PYK2 protein phosphorylated at tyrosine 881. Its advanced polyclonal antibody technology ensures high affinity and specificity, making it an ideal choice for researchers and clinicians studying PYK2 signaling pathways and associated cellular processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543449911576,"sku":"BT-AP07709","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_63dc2849-0896-49dc-b269-4986e180af0b.png?v=1705647771","url":"https:\/\/danabiosci.com\/products\/new-product-572791","provider":"Dana Bioscience","version":"1.0","type":"link"}