{"product_id":"new-product-572735","title":"PDGFR-beta(Phospho Tyr751) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer| composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12| that fuses this gene to that of the translocation| ETV6| leukemia gene| results in chronic myeloproliferative disorder with eosinophilia.\u003c\/p\u003e\n\u003cp\u003eThe PDGFR-beta(Phospho Tyr751) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PDGFR-beta protein phosphorylated at tyrosine 751 residue. This antibody is produced through a rigorous process of immunization and purification, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003ePDGFR-beta, a member of the platelet-derived growth factor receptor family, plays a crucial role in various cellular processes, including cell proliferation, differentiation, and migration. The phosphorylation of tyrosine 751 residue is known to be involved in the activation of downstream signaling pathways, leading to the regulation of these cellular processes.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody is validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent performance in detecting the phosphorylated form of PDGFR-beta in a wide range of sample types, including cell lysates and tissue sections.\u003cbr\u003e\u003cbr\u003eWith its high specificity and sensitivity, the PDGFR-beta(Phospho Tyr751) Polyclonal Antibody is an indispensable tool for researchers studying the role of PDGFR-beta phosphorylation in various physiological and pathological conditions. Its reliable performance and reproducibility make it an ideal choice for both basic research and clinical applications.\u003cbr\u003e\u003cbr\u003ePlease note that this product is for research use only and should not be used for diagnostic purposes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543438475544,"sku":"BT-AP07519","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_19ebcd56-a686-4ea4-9ccb-84e05a05c1e1.png?v=1705647491","url":"https:\/\/danabiosci.com\/products\/new-product-572735","provider":"Dana Bioscience","version":"1.0","type":"link"}