{"product_id":"new-product-572634","title":"NFκB-p65(Phospho Thr254) Polyclonal Antibody","description":"\u003cp\u003eNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor| NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL| RELA| or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene| RELA. Four transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe NFκB-p65(Phospho Thr254) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated NFκB-p65 at threonine 254 residue. This antibody is produced using advanced immunization techniques and exhibits exceptional affinity and selectivity towards the phosphorylated form of NFκB-p65.\u003cbr\u003e\u003cbr\u003eThe NFκB-p65 transcription factor plays a crucial role in various cellular processes, including inflammation, immune response, and cell survival. Phosphorylation of NFκB-p65 at threonine 254 residue has been implicated in the regulation of its transcriptional activity and nuclear translocation. Therefore, the ability to accurately measure the phosphorylation status of NFκB-p65 is of great importance in understanding its functional role in cellular signaling pathways.\u003cbr\u003e\u003cbr\u003eThe NFκB-p65(Phospho Thr254) Polyclonal Antibody offers outstanding performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated NFκB-p65 and other related proteins, ensuring reliable and specific detection of the phosphorylated form.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity and specificity, the NFκB-p65(Phospho Thr254) Polyclonal Antibody is an invaluable tool for researchers studying NFκB-p65 signaling pathways and its involvement in various diseases, such as cancer, autoimmune disorders, and inflammatory conditions. Its reliable performance and reproducibility make it an ideal choice for both basic research and clinical applications.\u003cbr\u003e\u003cbr\u003eIn summary, the NFκB-p65(Phospho Thr254) Polyclonal Antibody is a top-quality reagent that enables accurate and specific detection of phosphorylated NFκB-p65 at threonine 254 residue. Its exceptional performance and versatility make it an essential tool for researchers in the field of cellular signaling and disease biology.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543406592280,"sku":"BT-AP01247","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_2a3579e2-efc3-4100-9bc1-9ffa0d3794b9.png?v=1705646993","url":"https:\/\/danabiosci.com\/products\/new-product-572634","provider":"Dana Bioscience","version":"1.0","type":"link"}