{"product_id":"new-product-572629","title":"NFκB-p65(Phospho Ser311) Polyclonal Antibody","description":"\u003cp\u003eNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor| NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL| RELA| or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene| RELA. Four transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe NFκB-p65(Phospho Ser311) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NFκB-p65 protein phosphorylated at Ser311. This antibody is produced using advanced immunization techniques and exhibits exceptional affinity and selectivity towards the phosphorylated form of NFκB-p65. \u003cbr\u003e\u003cbr\u003eThe NFκB-p65 transcription factor plays a crucial role in the regulation of various cellular processes, including inflammation, immune response, and cell survival. Phosphorylation of NFκB-p65 at Ser311 has been implicated in the modulation of its transcriptional activity and downstream signaling pathways. Therefore, the ability to accurately measure the phosphorylation status of NFκB-p65 at Ser311 is of great importance in understanding the molecular mechanisms underlying these cellular processes.\u003cbr\u003e\u003cbr\u003eThe NFκB-p65(Phospho Ser311) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated NFκB-p65 and other related proteins, ensuring reliable and accurate results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a ready-to-use solution, allowing for convenient and efficient application in research laboratories. It is provided in a vial with optimal storage conditions to maintain its stability and functionality over an extended period.\u003cbr\u003e\u003cbr\u003eIn summary, the NFκB-p65(Phospho Ser311) Polyclonal Antibody is a valuable tool for researchers studying NFκB-p65 signaling pathways and its involvement in various cellular processes. Its high specificity, sensitivity, and ease of use make it an essential component in the investigation of phosphorylation events and their functional implications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543404593432,"sku":"BT-AP07296","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_30b001bc-8e7b-498a-957a-b5bb251c723d.png?v=1705646972","url":"https:\/\/danabiosci.com\/products\/new-product-572629","provider":"Dana Bioscience","version":"1.0","type":"link"}