{"product_id":"new-product-572499","title":"Caspase 2 Rabbit Polyclonal Antibody","description":"\u003cp\u003ealternative products:Isoforms differ in the N- and C-termini|Catalytic activity:Strict requirement for an Asp residue at P1| with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.|Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.|PTM:The mature protease can process its own propeptide| but not that of other caspases.|Belongs to the peptidase C14A family.|Contains 1 CARD domain.|subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers| each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.|tissue specificity:Expressed at higher levels in the embryonic lung| liver and kidney than in the heart and brain. In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle.|\u003c\/p\u003e\n\u003cp\u003eThe Caspase 2 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Caspase 2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Caspase 2 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.\u003cbr\u003e\u003cbr\u003eThe Caspase 2 Rabbit Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize Caspase 2 protein in human, mouse, and rat tissues and cell lines. The antibody has a high affinity and sensitivity, allowing for the detection of low levels of Caspase 2 protein in samples.\u003cbr\u003e\u003cbr\u003eThis antibody is an essential tool for researchers studying the role of Caspase 2 in various biological processes, including apoptosis, inflammation, and cancer. It can be used to investigate the expression and activation of Caspase 2 in different tissues and cell types, as well as to study the effects of Caspase 2 inhibitors and activators.\u003cbr\u003e\u003cbr\u003eIn summary, the Caspase 2 Rabbit Polyclonal Antibody is a reliable and high-quality reagent that provides accurate and reproducible results in various applications. Its specificity, sensitivity, and versatility make it an ideal choice for researchers studying Caspase 2 protein in different biological contexts.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543357407512,"sku":"BT-AP06906","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_a6f15046-b697-4b53-b6f8-8bb97df5e623.png?v=1705646389","url":"https:\/\/danabiosci.com\/products\/new-product-572499","provider":"Dana Bioscience","version":"1.0","type":"link"}