{"product_id":"new-product-572459","title":"IκB-alpha Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the NF-kappa-B inhibitor family| which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B\/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.\u003c\/p\u003e\n\u003cp\u003eThe IκB-alpha Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IκB-alpha protein in various biological samples. This antibody is produced through a rigorous process of immunization using a purified recombinant IκB-alpha protein as the antigen. It has been extensively validated for its specificity and affinity to ensure reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eThe IκB-alpha Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the phosphorylated and non-phosphorylated forms of IκB-alpha, enabling comprehensive analysis of the protein's regulation and function in cellular processes.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity, this antibody allows for the detection of low abundance IκB-alpha protein levels, making it an invaluable tool for researchers studying signal transduction pathways, inflammation, and immune response. Its versatility and reliability make it suitable for use in both basic research and clinical diagnostics.\u003cbr\u003e\u003cbr\u003eThe IκB-alpha Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming sample preparation. The antibody is available in various sizes to accommodate different experimental needs.\u003cbr\u003e\u003cbr\u003eIn summary, the IκB-alpha Polyclonal Antibody is a superior research tool that offers exceptional sensitivity, specificity, and versatility. Its reliable performance and ease of use make it an essential component in the study of IκB-alpha protein and its involvement in various biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543336042776,"sku":"BT-AP06782","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_1bddfe54-59c7-48d4-af4e-0e0c61b22f91.png?v=1705646192","url":"https:\/\/danabiosci.com\/products\/new-product-572459","provider":"Dana Bioscience","version":"1.0","type":"link"}