{"product_id":"new-product-572164","title":"EGFR(Phospho Tyr1016) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.\u003c\/p\u003e\n\u003cp\u003eThe EGFR(Phospho Tyr1016) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated tyrosine 1016 on the epidermal growth factor receptor (EGFR). This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target epitope.\u003cbr\u003e\u003cbr\u003eThe EGFR is a transmembrane receptor that plays a crucial role in cell growth, proliferation, and differentiation. Phosphorylation of tyrosine residues on the EGFR is a key event in the activation of downstream signaling pathways, leading to cellular responses such as cell survival, migration, and angiogenesis. The phosphorylation of tyrosine 1016 on the EGFR has been implicated in various pathological conditions, including cancer.\u003cbr\u003e\u003cbr\u003eThe EGFR(Phospho Tyr1016) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunoprecipitation, and immunohistochemistry. It exhibits minimal cross-reactivity with non-phosphorylated EGFR and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The EGFR(Phospho Tyr1016) Polyclonal Antibody is suitable for use in both research and clinical applications, enabling the investigation of EGFR signaling pathways and the development of targeted therapies.\u003cbr\u003e\u003cbr\u003eIn summary, the EGFR(Phospho Tyr1016) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of phosphorylated tyrosine 1016 on the EGFR. Its advanced polyclonal antibody technology ensures high affinity and specificity, making it an ideal choice for researchers and clinicians studying EGFR signaling and its implications in various diseases, particularly cancer.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543235477784,"sku":"BT-AP00569","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_b940081b-f607-4cc8-96d1-3c78e509c665.png?v=1705644814","url":"https:\/\/danabiosci.com\/products\/new-product-572164","provider":"Dana Bioscience","version":"1.0","type":"link"}