{"product_id":"new-product-572093","title":"cPLA2(Phospho Ser505) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids| including prostaglandins and leukotrienes| are lipid-based cellular hormones that regulate hemodynamics| inflammatory responses| and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation| resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe cPLA2(Phospho Ser505) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of cPLA2 phosphorylated at Ser505. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003ecPLA2, also known as cytosolic phospholipase A2, plays a crucial role in the release of arachidonic acid from membrane phospholipids. Phosphorylation of cPLA2 at Ser505 is a key regulatory event that modulates its enzymatic activity and subsequent downstream signaling pathways.\u003cbr\u003e\u003cbr\u003eThe cPLA2(Phospho Ser505) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated cPLA2 and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended to store the antibody at -20°C for long-term use to maintain its stability and activity.\u003cbr\u003e\u003cbr\u003eWith its exceptional specificity, sensitivity, and reliability, the cPLA2(Phospho Ser505) Polyclonal Antibody is an indispensable tool for researchers studying the role of cPLA2 phosphorylation in various biological processes and diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543201661208,"sku":"BT-AP00470","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e1a609ca-e01a-4e29-9697-a080847abdb4.png?v=1705644442","url":"https:\/\/danabiosci.com\/products\/new-product-572093","provider":"Dana Bioscience","version":"1.0","type":"link"}