{"product_id":"new-product-572026","title":"Chk1(Phospho Ser301) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene belongs to the Ser\/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR| two cell cycle proteins involved in DNA damage responses| that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe Chk1(Phospho Ser301) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Chk1 protein phosphorylated at Ser301. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.\u003cbr\u003e\u003cbr\u003eChk1 is a crucial protein involved in the regulation of cell cycle progression and DNA damage response. Phosphorylation of Chk1 at Ser301 plays a critical role in its activation and subsequent downstream signaling events. Therefore, the detection and analysis of Chk1 phosphorylation at Ser301 is of great importance in understanding the cellular response to DNA damage and its implications in various diseases, including cancer.\u003cbr\u003e\u003cbr\u003eThe Chk1(Phospho Ser301) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of Chk1 phosphorylation at Ser301 in a wide range of sample types.\u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. The Chk1(Phospho Ser301) Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing consistent and reproducible results.\u003cbr\u003e\u003cbr\u003eIn summary, the Chk1(Phospho Ser301) Polyclonal Antibody is an indispensable tool for researchers and scientists studying Chk1 signaling pathways and its involvement in cellular processes. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, facilitating groundbreaking discoveries in the field of molecular biology and beyond.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543171645720,"sku":"BT-AP01645","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_7a3f75b6-c6d8-4489-9890-77e8ef5d4122.png?v=1705644088","url":"https:\/\/danabiosci.com\/products\/new-product-572026","provider":"Dana Bioscience","version":"1.0","type":"link"}