Cdk5(Phospho Tyr15) Polyclonal Antibody

This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family| the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein| which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons| functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization| endocytosis and exocytosis| and apoptosis. In humans| an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.

The Cdk5(Phospho Tyr15) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Cdk5 protein phosphorylated at Tyr15 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Cdk5, also known as cyclin-dependent kinase 5, is a crucial regulator of cell cycle progression and neuronal development. Phosphorylation of Cdk5 at Tyr15 residue plays a significant role in modulating its activity and function. Therefore, the ability to accurately measure the phosphorylation status of Cdk5 at Tyr15 is of utmost importance in understanding its biological functions and associated signaling pathways.

The Cdk5(Phospho Tyr15) Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling precise detection and quantification of phosphorylated Cdk5 at Tyr15. It has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is manufactured using high-quality materials and rigorous quality control measures to ensure consistent and reliable performance. It is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage.

In summary, the Cdk5(Phospho Tyr15) Polyclonal Antibody is an indispensable tool for researchers studying the role of Cdk5 phosphorylation in cellular processes and neurological disorders. Its high specificity, sensitivity, and versatility make it an ideal choice for a wide range of experimental applications.