{"product_id":"new-product-572010","title":"CDH3 Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats| a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition| aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia| ectrodactyly| and macular dystrophy syndrome (EEMS).\u003c\/p\u003e\n\u003cp\u003eThe CDH3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of CDH3 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards CDH3. \u003cbr\u003e\u003cbr\u003eCDH3, also known as P-cadherin, is a calcium-dependent cell adhesion molecule that plays a crucial role in cell-cell adhesion and tissue morphogenesis. It is primarily expressed in epithelial tissues and is involved in various physiological and pathological processes, including embryonic development, tissue remodeling, and cancer progression. \u003cbr\u003e\u003cbr\u003eThe CDH3 Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of CDH3 protein expression in both normal and diseased tissues. \u003cbr\u003e\u003cbr\u003eThis antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimal wastage. The CDH3 Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings. \u003cbr\u003e\u003cbr\u003eWith its exceptional performance and versatility, the CDH3 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying CDH3 protein expression and its implications in various biological processes and diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543164764440,"sku":"BT-AP01449","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_afee2934-ba14-4111-886c-81469bd644d7.png?v=1705644000","url":"https:\/\/danabiosci.com\/products\/new-product-572010","provider":"Dana Bioscience","version":"1.0","type":"link"}