{"product_id":"new-product-571944","title":"Caspase 3 Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits| large and small| that dimerize to form the active enzyme. This protein cleaves and activates caspases 6| 7 and 9| and the protein itself is processed by caspases 8| 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein| which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.\u003c\/p\u003e\n\u003cp\u003eThe CASPASE 3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CASPASE 3 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the CASPASE 3 protein. It has been extensively validated for its specificity and affinity towards CASPASE 3, ensuring reliable and accurate results.\u003cbr\u003e\u003cbr\u003eThe CASPASE 3 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the proenzyme and the active form of CASPASE 3, enabling the detection of total CASPASE 3 protein levels as well as its activation status. This antibody demonstrates minimal cross-reactivity with other caspases, ensuring specific and precise detection of CASPASE 3.\u003cbr\u003e\u003cbr\u003eWith its high sensitivity, the CASPASE 3 Polyclonal Antibody allows for the detection of low-abundance CASPASE 3 protein in samples with limited availability. It offers a reliable and reproducible solution for researchers studying apoptosis, as CASPASE 3 plays a crucial role in this process. The antibody's robust performance and consistent results make it an ideal choice for both basic research and clinical applications.\u003cbr\u003e\u003cbr\u003eThe CASPASE 3 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effective and efficient experiments. The antibody is manufactured under strict quality control standards, guaranteeing batch-to-batch consistency and reliability.\u003cbr\u003e\u003cbr\u003eIn summary, the CASPASE 3 Polyclonal Antibody is a highly specific and sensitive tool that enables accurate detection and quantification of CASPASE 3 protein. Its exceptional performance, versatility, and reliability make it an invaluable asset for researchers in the field of apoptosis and beyond.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543142121752,"sku":"BT-AP00227","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_91dcca9f-2abd-4951-ac3a-1961257ee787.png?v=1705643693","url":"https:\/\/danabiosci.com\/products\/new-product-571944","provider":"Dana Bioscience","version":"1.0","type":"link"}