{"product_id":"new-product-571943","title":"Caspase 3 p17 Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits| large and small| that dimerize to form the active enzyme. This protein cleaves and activates caspases 6| 7 and 9| and the protein itself is processed by caspases 8| 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein| which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.\u003c\/p\u003e\n\u003cp\u003eThe Caspase 3 p17 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Caspase 3 p17 protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Caspase 3 p17 Polyclonal Antibody is a valuable tool for researchers studying apoptosis and cell death pathways. Caspase 3 is a key enzyme involved in the execution phase of apoptosis, and the p17 fragment is a well-established marker of Caspase 3 activation. This antibody is capable of detecting the p17 fragment of Caspase 3 with high specificity and sensitivity, making it an ideal choice for researchers looking to study the role of Caspase 3 in apoptosis and other cellular processes.\u003cbr\u003e\u003cbr\u003eThe Caspase 3 p17 Polyclonal Antibody is manufactured to the highest standards of quality and purity, ensuring consistent and reliable results in every experiment. It is supplied in a convenient format, with a range of sizes available to suit the needs of different research projects. With its high specificity, sensitivity, and versatility, the Caspase 3 p17 Polyclonal Antibody is an essential tool for any researcher studying apoptosis and cell death pathways.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543141859608,"sku":"BT-AP00226","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_83e7ad18-cbec-4c4a-8de8-3828edab040b.png?v=1705643681","url":"https:\/\/danabiosci.com\/products\/new-product-571943","provider":"Dana Bioscience","version":"1.0","type":"link"}