{"product_id":"new-product-571921","title":"c-Rel(Phospho Ser503) Polyclonal Antibody","description":"\u003cp\u003eThis gene encodes a protein that belongs to the Rel homology domain\/immunoglobulin-like fold| plexin| transcription factor (RHD\/IPT) family. Members of this family regulate genes involved in apoptosis| inflammation| the immune response| and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas| including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\u003cp\u003eThe c-Rel(Phospho Ser503) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of c-Rel protein phosphorylated at Ser503. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eThe c-Rel protein is a member of the Rel\/NF-κB family of transcription factors, which play crucial roles in various cellular processes, including immune response, inflammation, and cell survival. Phosphorylation of c-Rel at Ser503 has been shown to regulate its activity and nuclear translocation, thereby influencing its transcriptional activity and downstream signaling pathways.\u003cbr\u003e\u003cbr\u003eThis polyclonal antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThe c-Rel(Phospho Ser503) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy integration into various experimental protocols. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.\u003cbr\u003e\u003cbr\u003eResearchers and scientists can confidently utilize this antibody to investigate the phosphorylation status and functional implications of c-Rel protein in their studies. Its high specificity and sensitivity make it an invaluable tool for understanding the intricate regulatory mechanisms of c-Rel and its involvement in various biological processes.\u003cbr\u003e\u003cbr\u003eIn summary, the c-Rel(Phospho Ser503) Polyclonal Antibody is a reliable and efficient reagent for the detection and analysis of phosphorylated c-Rel protein. Its exceptional performance and versatility make it an essential tool for researchers in the fields of immunology, inflammation, and cellular signaling.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543134585112,"sku":"BT-AP00760","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_b78cf775-e5c8-4cfa-9013-bd713ca9d3d8.png?v=1705643567","url":"https:\/\/danabiosci.com\/products\/new-product-571921","provider":"Dana Bioscience","version":"1.0","type":"link"}