{"product_id":"new-product-571920","title":"c-Myc(Phospho Ser62) Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by this gene is a multifunctional| nuclear phosphoprotein that plays a role in cell cycle progression| apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations| overexpression| rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors| leukemias and lymphomas| including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream| in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas| suggesting its importance in the normal function of this gene.\u003c\/p\u003e\n\u003cp\u003eThe c-Myc(Phospho Ser62) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated c-Myc at Serine 62 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003ec-Myc is a transcription factor that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Phosphorylation of c-Myc at Serine 62 has been shown to regulate its stability, subcellular localization, and transcriptional activity. Therefore, the detection and quantification of phosphorylated c-Myc at Serine 62 are of great importance in understanding the molecular mechanisms underlying these cellular processes.\u003cbr\u003e\u003cbr\u003eThe c-Myc(Phospho Ser62) Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results. This antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and cultured cells.\u003cbr\u003e\u003cbr\u003eWith its superior quality and performance, the c-Myc(Phospho Ser62) Polyclonal Antibody is an indispensable tool for researchers and scientists working in the fields of cancer biology, cell signaling, and molecular biology. Its ability to specifically detect and quantify phosphorylated c-Myc at Serine 62 provides valuable insights into the intricate regulatory mechanisms governing cellular processes, ultimately contributing to the advancement of scientific knowledge and the development of novel therapeutic strategies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543134355736,"sku":"BT-AP00729","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f1d28864-eb0d-4cf2-9f18-abc290b9b70f.png?v=1705643563","url":"https:\/\/danabiosci.com\/products\/new-product-571920","provider":"Dana Bioscience","version":"1.0","type":"link"}