{"product_id":"new-product-571877","title":"IGF-I Receptor beta(Phospho-Tyr1131) Rabbit Polyclonal Antibody","description":"\u003cp\u003eThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.\u003c\/p\u003e\n\u003cp\u003eThe IGF-I Receptor beta(Phospho-Tyr1131) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of the phosphorylated form of the IGF-I receptor beta subunit at tyrosine 1131. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability.\u003cbr\u003e\u003cbr\u003eThe IGF-I receptor plays a crucial role in various cellular processes, including cell growth, differentiation, and survival. Phosphorylation of the receptor at specific tyrosine residues, such as Tyr1131, is a key event in the activation of downstream signaling pathways. Therefore, the ability to detect and quantify the phosphorylated form of the IGF-I receptor beta subunit is essential for understanding its functional role in cellular processes.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry. It exhibits minimal cross-reactivity with non-phosphorylated forms of the IGF-I receptor beta subunit, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThe IGF-I Receptor beta(Phospho-Tyr1131) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready to use for immediate application. It is provided in a convenient size, allowing for multiple experiments and ensuring cost-effectiveness.\u003cbr\u003e\u003cbr\u003eIn summary, the IGF-I Receptor beta(Phospho-Tyr1131) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of the phosphorylated form of the IGF-I receptor beta subunit. Its excellent performance, reliability, and versatility make it an ideal choice for researchers studying the functional role of the IGF-I receptor in various cellular processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543115481368,"sku":"BT-AP00099","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_e08639ae-1aca-442e-927a-39dc5e063402.png?v=1705643372","url":"https:\/\/danabiosci.com\/products\/new-product-571877","provider":"Dana Bioscience","version":"1.0","type":"link"}