{"product_id":"new-product-571809","title":"Phospho-Bcl-2 (T74) Polyclonal Antibody","description":"\u003cp\u003eBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe Phospho-Bcl-2 (T74) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Bcl-2 protein at threonine 74 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional quality and reliability.\u003cbr\u003e\u003cbr\u003eBcl-2 is a key regulator of apoptosis, playing a crucial role in maintaining cellular homeostasis. Phosphorylation of Bcl-2 at threonine 74 has been implicated in various cellular processes, including cell survival, proliferation, and differentiation. The Phospho-Bcl-2 (T74) Polyclonal Antibody enables researchers to investigate the phosphorylation status of Bcl-2 at this specific site, providing valuable insights into its functional significance.\u003cbr\u003e\u003cbr\u003eThis antibody exhibits high specificity towards phosphorylated Bcl-2 (T74) and demonstrates minimal cross-reactivity with non-phosphorylated Bcl-2 or other related proteins. It has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The antibody's exceptional sensitivity allows for the detection of even low levels of phosphorylated Bcl-2, facilitating accurate and reliable quantification.\u003cbr\u003e\u003cbr\u003eThe Phospho-Bcl-2 (T74) Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming preparation steps. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and cultured cells.\u003cbr\u003e\u003cbr\u003eResearchers can rely on the Phospho-Bcl-2 (T74) Polyclonal Antibody to deliver consistent and reproducible results, enabling them to advance their understanding of Bcl-2 phosphorylation and its implications in various biological processes. With its exceptional specificity, sensitivity, and versatility, this antibody is an indispensable tool for any researcher studying Bcl-2 signaling pathways and its role in disease progression.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543077339416,"sku":"BT-PHS01121","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_87a5f368-264c-4135-9093-815e92d927da.png?v=1705643010","url":"https:\/\/danabiosci.com\/products\/new-product-571809","provider":"Dana Bioscience","version":"1.0","type":"link"}