{"product_id":"new-product-571785","title":"Phospho-Actin- Alpha\/Gamma (Y55\/53) Polyclonal Antibody","description":"\u003cp\u003eActins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin  (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by ACTC1 (actin, alpha, cardiac muscle 1) belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in ACTC1 have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).\u003c\/p\u003e\n\u003cp\u003eThe Phospho-Actin-Alpha\/Gamma (Y55\/53) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of phosphorylated Actin-Alpha and Actin-Gamma proteins. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications.\u003cbr\u003e\u003cbr\u003eThe Phospho-Actin-Alpha\/Gamma (Y55\/53) Polyclonal Antibody exhibits a high affinity towards the phosphorylated forms of Actin-Alpha and Actin-Gamma, making it an ideal choice for researchers studying cellular processes involving actin cytoskeleton dynamics and signaling pathways. It recognizes the phosphorylation sites at tyrosine residues 55 and 53, enabling precise and accurate detection of the phosphorylated forms of these proteins.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated for use in immunoblotting, immunoprecipitation, immunofluorescence, and immunohistochemistry techniques. Its exceptional specificity ensures minimal cross-reactivity with non-phosphorylated forms of Actin-Alpha and Actin-Gamma, resulting in reliable and reproducible results.\u003cbr\u003e\u003cbr\u003eThe Phospho-Actin-Alpha\/Gamma (Y55\/53) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex antibody preparation procedures. It is provided in a convenient format, allowing for easy integration into various experimental protocols.\u003cbr\u003e\u003cbr\u003eWith its superior performance and versatility, the Phospho-Actin-Alpha\/Gamma (Y55\/53) Polyclonal Antibody is an indispensable tool for researchers investigating the role of phosphorylated Actin-Alpha and Actin-Gamma in cellular processes and disease mechanisms. Its high sensitivity, specificity, and ease of use make it an excellent choice for both basic research and clinical applications.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543065182488,"sku":"BT-PHS00977","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_08b01242-1f28-43cd-b2e5-c2a27fc18359.png?v=1705642904","url":"https:\/\/danabiosci.com\/products\/new-product-571785","provider":"Dana Bioscience","version":"1.0","type":"link"}