{"product_id":"new-product-571770","title":"Phospho-ALK (Y1604) Polyclonal Antibody","description":"\u003cp\u003eALK encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. ALK tyrosine kinase receptor comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)\/EML4 (chromosome 2), ALK\/RANBP2 (chromosome 2), ALK\/ATIC (chromosome 2), ALK\/TFG (chromosome 3), ALK\/NPM1 (chromosome 5), ALK\/SQSTM1 (chromosome 5), ALK\/KIF5B (chromosome 10), ALK\/CLTC (chromosome 17), ALK\/TPM4 (chromosome 19), and ALK\/MSN (chromosome X).\u003c\/p\u003e\n\u003cp\u003eIntroducing the Phospho-ALK (Y1604) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate accurate detection and analysis of phosphorylated anaplastic lymphoma kinase (ALK) at tyrosine residue 1604. This high-quality antibody is specifically engineered to exhibit exceptional sensitivity and specificity, enabling researchers to delve into the intricate mechanisms underlying ALK signaling pathways.\u003cbr\u003e\u003cbr\u003eCrafted with utmost precision, the Phospho-ALK (Y1604) Polyclonal Antibody boasts an advanced polyclonal design, ensuring optimal performance across a wide range of applications, including Western blotting, immunoprecipitation, and immunohistochemistry. Its remarkable affinity for phosphorylated ALK at Y1604 guarantees reliable and reproducible results, empowering scientists to unravel the complexities of ALK-related cellular processes with utmost confidence.\u003cbr\u003e\u003cbr\u003eThe Phospho-ALK (Y1604) Polyclonal Antibody is meticulously validated through rigorous quality control measures, assuring researchers of its exceptional reliability and consistency. Its exceptional specificity ensures minimal cross-reactivity with non-phosphorylated ALK and other related proteins, thereby minimizing false-positive results and enhancing experimental accuracy.\u003cbr\u003e\u003cbr\u003eThis antibody is meticulously manufactured using state-of-the-art techniques and adheres to the highest industry standards, ensuring unparalleled performance and reproducibility. Its robust formulation guarantees long-term stability, allowing for extended usage without compromising its exceptional quality.\u003cbr\u003e\u003cbr\u003eIn summary, the Phospho-ALK (Y1604) Polyclonal Antibody represents a breakthrough in scientific research, providing researchers with an indispensable tool to investigate the intricate phosphorylation events associated with ALK at tyrosine residue 1604. With its exceptional sensitivity, specificity, and reliability, this antibody is poised to revolutionize the understanding of ALK signaling pathways and contribute to advancements in the field of oncology and beyond.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543056630040,"sku":"BT-PHS00898","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_52342832-e08d-4a73-8d1d-d0bd5436b3f4.png?v=1705642836","url":"https:\/\/danabiosci.com\/products\/new-product-571770","provider":"Dana Bioscience","version":"1.0","type":"link"}