{"product_id":"new-product-571765","title":"Phospho-Amyloid-Beta (T743) Polyclonal Antibody","description":"\u003cp\u003eAPP encodes a cell surface receptor and transmembrane precursor protein (amyloid beta precursor protein) that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1\/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in APP have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for APP.\u003c\/p\u003e\n\u003cp\u003eIntroducing the Phospho-Amyloid-Beta (T743) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of neurodegenerative disorders. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, enabling precise detection and analysis of phosphorylated amyloid-beta (T743) protein.\u003cbr\u003e\u003cbr\u003eCrafted with utmost precision and utilizing state-of-the-art technology, this antibody offers researchers an invaluable resource for investigating the intricate mechanisms underlying amyloid-beta pathology. Its polyclonal nature ensures a diverse range of epitope recognition, enhancing the versatility and reliability of experimental outcomes.\u003cbr\u003e\u003cbr\u003eThe Phospho-Amyloid-Beta (T743) Polyclonal Antibody demonstrates unparalleled affinity towards phosphorylated amyloid-beta (T743), enabling the detection of even minute quantities of this crucial protein. This antibody's exceptional sensitivity empowers researchers to delve into the intricate phosphorylation events associated with amyloid-beta, unraveling the complex interplay between this protein and neurodegenerative processes.\u003cbr\u003e\u003cbr\u003eFurthermore, this antibody's exceptional specificity ensures minimal cross-reactivity, guaranteeing accurate and reliable results. Its robust performance in various applications, including immunohistochemistry, immunofluorescence, and Western blotting, further solidifies its status as an indispensable tool for comprehensive amyloid-beta research.\u003cbr\u003e\u003cbr\u003eIn summary, the Phospho-Amyloid-Beta (T743) Polyclonal Antibody represents a breakthrough in the field of neurodegenerative disorder research. Its exceptional specificity, sensitivity, and versatility make it an indispensable asset for scientists seeking to unravel the intricate molecular mechanisms underlying amyloid-beta pathology. With this antibody, researchers can confidently embark on groundbreaking studies, paving the way for novel therapeutic interventions and a deeper understanding of neurodegenerative diseases.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543054401816,"sku":"BT-PHS00855","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_0b381655-b460-44f0-84da-4b154610a8db.png?v=1705642817","url":"https:\/\/danabiosci.com\/products\/new-product-571765","provider":"Dana Bioscience","version":"1.0","type":"link"}