{"product_id":"new-product-571763","title":"Phospho-14-3-3 Zeta (S58) Polyclonal Antibody","description":"\u003cp\u003eTyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein zeta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. Tyrosine 3-monooxygenase\/tryptophan 5-monooxygenase activation protein zeta interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for YWHAZ.\u003c\/p\u003e\n\u003cp\u003eThe Phospho-14-3-3 Zeta (S58) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated 14-3-3 Zeta protein at serine 58 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eThe 14-3-3 Zeta protein plays a crucial role in various cellular processes, including signal transduction, cell cycle regulation, and apoptosis. Phosphorylation of the serine 58 residue has been implicated in the modulation of 14-3-3 Zeta protein function and its interaction with other proteins. Therefore, the Phospho-14-3-3 Zeta (S58) Polyclonal Antibody serves as an invaluable tool for researchers studying the regulatory mechanisms and functional implications of 14-3-3 Zeta phosphorylation.\u003cbr\u003e\u003cbr\u003eThis antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated 14-3-3 Zeta protein and other related proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThe Phospho-14-3-3 Zeta (S58) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy integration into various experimental protocols. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.\u003cbr\u003e\u003cbr\u003eWith its exceptional specificity, sensitivity, and versatility, the Phospho-14-3-3 Zeta (S58) Polyclonal Antibody is an indispensable tool for researchers investigating the role of 14-3-3 Zeta phosphorylation in cellular processes. Its reliable performance and ease of use make it an ideal choice for both basic research and drug development studies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543053746456,"sku":"BT-PHS00853","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_868f0f96-d235-4aa2-924c-96f4dc15b4d9.png?v=1705642809","url":"https:\/\/danabiosci.com\/products\/new-product-571763","provider":"Dana Bioscience","version":"1.0","type":"link"}