{"product_id":"new-product-571709","title":"Phospho-Akt (T308) Polyclonal Antibody","description":"\u003cp\u003eThe serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine\/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in AKT1 have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for AKT1.\u003c\/p\u003e\n\u003cp\u003eIntroducing the Phospho-Akt (T308) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate accurate and reliable detection of phosphorylated Akt at threonine 308 residue. This high-quality antibody, crafted with utmost precision, exhibits exceptional specificity and sensitivity, enabling researchers to delve into the intricate mechanisms underlying Akt signaling pathways.\u003cbr\u003e\u003cbr\u003eThe Phospho-Akt (T308) Polyclonal Antibody boasts an unparalleled affinity for phosphorylated Akt at threonine 308, ensuring optimal recognition and binding. Its robust performance guarantees precise identification and quantification of phosphorylated Akt, thereby facilitating comprehensive investigations into cellular processes influenced by Akt activation.\u003cbr\u003e\u003cbr\u003eThis antibody, meticulously developed through rigorous research and development processes, adheres to the highest industry standards, ensuring reproducibility and consistency across experiments. Its exceptional specificity eliminates the risk of cross-reactivity, enabling researchers to confidently explore Akt signaling pathways with utmost accuracy.\u003cbr\u003e\u003cbr\u003eFurthermore, the Phospho-Akt (T308) Polyclonal Antibody exhibits remarkable sensitivity, enabling detection of even low levels of phosphorylated Akt. This attribute empowers researchers to unravel subtle changes in Akt activation, thereby unraveling the intricate dynamics of cellular signaling events.\u003cbr\u003e\u003cbr\u003eThe Phospho-Akt (T308) Polyclonal Antibody is compatible with a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for seamless integration into diverse experimental setups, facilitating comprehensive investigations across various research domains.\u003cbr\u003e\u003cbr\u003eIn summary, the Phospho-Akt (T308) Polyclonal Antibody represents a pinnacle of scientific innovation, offering researchers an invaluable tool to unravel the complexities of Akt signaling pathways. With its exceptional specificity, sensitivity, and compatibility, this antibody empowers scientists to unlock new insights into cellular processes influenced by Akt activation.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543023272216,"sku":"BT-PHS00490","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_dc81dc72-2faf-4f32-8afb-1b23d0a21916.png?v=1705642518","url":"https:\/\/danabiosci.com\/products\/new-product-571709","provider":"Dana Bioscience","version":"1.0","type":"link"}