{"product_id":"new-product-571679","title":"Phospho-Btk (Y551) Polyclonal Antibody","description":"\u003cp\u003eBruton tyrosine kinase encoded by BTK plays a crucial role in B-cell development. Mutations in BTK cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\u003cp\u003eThe Phospho-Btk (Y551) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Bruton's tyrosine kinase (Btk) at the tyrosine 551 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional quality and reliability.\u003cbr\u003e\u003cbr\u003eBruton's tyrosine kinase (Btk) is a crucial signaling molecule involved in B-cell receptor (BCR) signaling pathway. Phosphorylation of Btk at the tyrosine 551 residue is known to play a critical role in the activation and regulation of Btk activity. Therefore, the Phospho-Btk (Y551) Polyclonal Antibody serves as an invaluable tool for researchers studying Btk signaling and its associated cellular processes.\u003cbr\u003e\u003cbr\u003eThis antibody exhibits exceptional specificity towards the phosphorylated form of Btk at the tyrosine 551 residue, enabling precise and accurate detection of this critical phosphorylation event. It has been extensively validated for various applications, including Western blotting, immunoprecipitation, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eThe Phospho-Btk (Y551) Polyclonal Antibody is manufactured using state-of-the-art techniques, ensuring high sensitivity and reproducibility. It is produced in a controlled environment by experienced scientists, following strict quality control measures to guarantee batch-to-batch consistency.\u003cbr\u003e\u003cbr\u003eWith its exceptional specificity and sensitivity, the Phospho-Btk (Y551) Polyclonal Antibody is an indispensable tool for researchers investigating Btk signaling pathways and its implications in various diseases, including B-cell malignancies and autoimmune disorders. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.\u003cbr\u003e\u003cbr\u003eIn summary, the Phospho-Btk (Y551) Polyclonal Antibody is a highly specific and sensitive antibody that enables precise detection and analysis of phosphorylated Btk at the tyrosine 551 residue. Its exceptional quality, reliability, and versatility make it an essential tool for researchers in the field of Btk signaling and related studies.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543011475736,"sku":"BT-PHS00288","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_14843fdf-ef6f-4041-b5b9-5b7f9eac8490.png?v=1705642360","url":"https:\/\/danabiosci.com\/products\/new-product-571679","provider":"Dana Bioscience","version":"1.0","type":"link"}