{"product_id":"new-product-571665","title":"Phospho-Calnexin (S583) Polyclonal Antibody","description":"\u003cp\u003eCANX encodes a member of the calnexin family of molecular chaperones. Calnexin is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described\u003c\/p\u003e\n\u003cp\u003eThe Phospho-Calnexin (S583) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Calnexin protein. Calnexin, an integral membrane protein residing in the endoplasmic reticulum (ER), plays a crucial role in protein folding and quality control within the ER. This polyclonal antibody has been meticulously developed and validated to specifically recognize the phosphorylated form of Calnexin at serine 583 residue.\u003cbr\u003e\u003cbr\u003eWith its exceptional specificity, this antibody enables researchers to investigate the phosphorylation status of Calnexin in various biological samples. It offers a reliable and accurate means to explore the regulatory mechanisms and functional implications of Calnexin phosphorylation in cellular processes such as protein folding, ER stress response, and protein trafficking.\u003cbr\u003e\u003cbr\u003eThe Phospho-Calnexin (S583) Polyclonal Antibody exhibits outstanding sensitivity, allowing for the detection of low abundance phosphorylated Calnexin in complex samples. Its robust performance ensures reliable and reproducible results, making it an ideal choice for both qualitative and quantitative analyses.\u003cbr\u003e\u003cbr\u003eThis antibody has been extensively validated using various experimental techniques, including Western blotting, immunoprecipitation, and immunofluorescence. It demonstrates excellent performance across a wide range of species, including human, mouse, and rat, making it suitable for diverse research applications.\u003cbr\u003e\u003cbr\u003eFurthermore, this polyclonal antibody has been rigorously tested for its specificity, ensuring minimal cross-reactivity with non-phosphorylated Calnexin or other related proteins. Its high affinity and selectivity guarantee accurate and precise detection of phosphorylated Calnexin, minimizing false-positive results.\u003cbr\u003e\u003cbr\u003eThe Phospho-Calnexin (S583) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy integration into existing laboratory protocols.\u003cbr\u003e\u003cbr\u003eIn summary, the Phospho-Calnexin (S583) Polyclonal Antibody is a reliable and versatile tool for the investigation of phosphorylated Calnexin. Its exceptional specificity, sensitivity, and robust performance make it an invaluable asset for researchers studying protein folding, ER stress response, and protein trafficking.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47543005643032,"sku":"BT-PHS00041","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_7b69e7ff-1d48-464b-bf64-f84e878bfab3.png?v=1705642288","url":"https:\/\/danabiosci.com\/products\/new-product-571665","provider":"Dana Bioscience","version":"1.0","type":"link"}