{"product_id":"new-product-571648","title":"Phospho-ATF-2 (S62) Polyclonal Antibody","description":"\u003cp\u003eATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins. Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Activating transcription factor 2 binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this ATF2.\u003c\/p\u003e\n\u003cp\u003eThe Phospho-ATF-2 (S62) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of phosphorylated ATF-2 protein at serine 62 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.\u003cbr\u003e\u003cbr\u003eATF-2, also known as activating transcription factor 2, is a key transcription factor involved in cellular responses to stress and various signaling pathways. Phosphorylation of ATF-2 at serine 62 residue plays a crucial role in its activation and subsequent regulation of gene expression. Therefore, the Phospho-ATF-2 (S62) Polyclonal Antibody serves as an invaluable tool for researchers studying the intricate mechanisms underlying cellular stress responses and gene regulation.\u003cbr\u003e\u003cbr\u003eThis antibody exhibits outstanding performance in Western blotting, enabling the detection of phosphorylated ATF-2 protein with high sensitivity and specificity. It recognizes the phosphorylated serine 62 residue of ATF-2, while exhibiting minimal cross-reactivity with non-phosphorylated ATF-2 or other related proteins. This specificity ensures accurate and reliable results, facilitating precise quantification and analysis of ATF-2 phosphorylation levels.\u003cbr\u003e\u003cbr\u003eFurthermore, the Phospho-ATF-2 (S62) Polyclonal Antibody demonstrates excellent performance in immunohistochemistry and immunofluorescence applications. It enables the visualization and localization of phosphorylated ATF-2 within cells and tissues, providing valuable insights into its spatial distribution and potential functional roles in various biological processes.\u003cbr\u003e\u003cbr\u003eThe Phospho-ATF-2 (S62) Polyclonal Antibody is manufactured under stringent quality control standards, ensuring batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. The antibody is provided in a convenient format, allowing for easy storage and handling.\u003cbr\u003e\u003cbr\u003eIn summary, the Phospho-ATF-2 (S62) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of phosphorylated ATF-2 protein. Its exceptional sensitivity and specificity, along with its compatibility with various applications, make it an indispensable asset for researchers investigating cellular stress responses, gene regulation, and related biological processes.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542991454488,"sku":"BT-PHS00024","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_824b1629-b274-4841-8132-4b667a8ea63a.png?v=1705642194","url":"https:\/\/danabiosci.com\/products\/new-product-571648","provider":"Dana Bioscience","version":"1.0","type":"link"}