{"product_id":"new-product-571428","title":"USP45 Polyclonal Antibody","description":"\u003cp\u003eThe ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. A wide range of enzymes facilitate the proteolytic Ub pathway, including USPs (ubiquitin specific peptidases), which are cysteine proteases that are responsible for the release of ubiquitin from a ubiquitylated substrate and precursor fusion proteins. USP45 (Ubiquitin carboxyl-terminal hydrolase 45), also known as Deubiquitinating enzyme 45, is a 819 amino acid protein that is involved in ubiquitin-dependent protein catabolism. USP45 differs from other USPs in that it contains a UBP-type zinc finger, a domain which binds ubiquitin. Although USP45 is broadly expressed, the highest levels can be found in skeletal muscle, spleen and ovary. There are three isoforms of USP45 which are produced as a result of alternative splicing.\u003c\/p\u003e\n\u003cp\u003eThe USP45 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of USP45 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, ensuring its exceptional sensitivity and specificity.\u003cbr\u003e\u003cbr\u003eThe USP45 Polyclonal Antibody exhibits a broad range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the role of USP45 in cellular processes, such as protein degradation, DNA repair, and cell cycle regulation.\u003cbr\u003e\u003cbr\u003eWith its superior performance, this antibody guarantees accurate and reproducible results, making it an indispensable tool for both basic research and clinical studies. Its high affinity and low background ensure minimal interference, allowing for precise and reliable quantification of USP45 protein levels.\u003cbr\u003e\u003cbr\u003eFurthermore, the USP45 Polyclonal Antibody has been rigorously validated to ensure its consistent performance across different experimental conditions. It exhibits excellent stability, enabling long-term storage without compromising its quality.\u003cbr\u003e\u003cbr\u003eIn summary, the USP45 Polyclonal Antibody is a cutting-edge research tool that offers exceptional sensitivity, specificity, and versatility. Its reliable performance and broad range of applications make it an invaluable asset for scientists and researchers in the field of molecular biology and beyond.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542897508632,"sku":"BT-AP09447","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f7ae88e4-2c29-462c-b1b4-f34b9604f92f.png?v=1705641067","url":"https:\/\/danabiosci.com\/products\/new-product-571428","provider":"Dana Bioscience","version":"1.0","type":"link"}