{"product_id":"new-product-571334","title":"TSLC1 Polyclonal Antibody","description":"\u003cp\u003eCADM1 (Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases associated with CADM1 include asthenopia and lung cancer. Among its related pathways are Cell junction organization and Cell adhesion molecules (CAMs). Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and PDZ domain binding. An important paralog of this gene is CADM3. Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.\u003c\/p\u003e\n\u003cp\u003eThe TSLC1 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The TSLC1 Polyclonal Antibody is ideal for use in immunohistochemistry, western blotting, and other applications where high sensitivity and specificity are required.\u003cbr\u003e\u003cbr\u003eThis antibody is designed to target TSLC1, a tumor suppressor gene that is involved in the regulation of cell growth and differentiation. The TSLC1 Polyclonal Antibody is highly specific for TSLC1 and does not cross-react with other proteins, ensuring accurate and reliable results.\u003cbr\u003e\u003cbr\u003eThe TSLC1 Polyclonal Antibody is produced using state-of-the-art techniques and is rigorously tested to ensure its quality and performance. This antibody is supplied in a convenient format and is ready to use in a variety of applications.\u003cbr\u003e\u003cbr\u003eOverall, the TSLC1 Polyclonal Antibody is a reliable and effective tool for researchers studying TSLC1 and its role in cancer biology. Its high specificity and sensitivity make it an ideal choice for a wide range of applications, and its quality and performance are guaranteed.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542864871704,"sku":"BT-AP09266","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_51392bbd-ef9f-479e-af0f-866203758eef.png?v=1705640539","url":"https:\/\/danabiosci.com\/products\/new-product-571334","provider":"Dana Bioscience","version":"1.0","type":"link"}