{"product_id":"new-product-571274","title":"TRAF1 Polyclonal Antibody","description":"\u003cp\u003eThe protein encoded by TRAF1 (TNF receptor associated factor 1) is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8\/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for TRAF1.\u003c\/p\u003e\n\u003cp\u003eThe TRAF1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of TRAF1 protein expression in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.\u003cbr\u003e\u003cbr\u003eTRAF1, also known as TNF receptor-associated factor 1, is a key regulator of multiple signaling pathways involved in immune responses and inflammation. It plays a crucial role in the activation of NF-κB and MAPK signaling cascades, which are essential for cell survival, proliferation, and differentiation.\u003cbr\u003e\u003cbr\u003eThe TRAF1 Polyclonal Antibody exhibits exceptional specificity towards TRAF1 protein, enabling accurate and reliable detection in Western blotting, immunohistochemistry, and immunofluorescence applications. It recognizes both endogenous and recombinant TRAF1 protein, making it suitable for a wide range of experimental settings.\u003cbr\u003e\u003cbr\u003eThis antibody demonstrates excellent sensitivity, allowing for the detection of low levels of TRAF1 protein expression. It exhibits minimal cross-reactivity with other related proteins, ensuring precise and specific results. The TRAF1 Polyclonal Antibody is validated for use in various species, including human, mouse, and rat, making it a versatile tool for researchers working with different model systems.\u003cbr\u003e\u003cbr\u003eThe TRAF1 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The antibody is stored at -20°C, maintaining its stability and functionality for an extended period.\u003cbr\u003e\u003cbr\u003eIn summary, the TRAF1 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of TRAF1 protein expression. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers studying immune responses, inflammation, and related signaling pathways.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542852682008,"sku":"BT-AP09167","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_9eed1d99-b72e-4540-b480-95dae620e1a4.png?v=1705640258","url":"https:\/\/danabiosci.com\/products\/new-product-571274","provider":"Dana Bioscience","version":"1.0","type":"link"}