{"product_id":"new-product-571128","title":"TCF-3 Polyclonal Antibody","description":"\u003cp\u003eTCF3 encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.\u003c\/p\u003e\n\u003cp\u003eThe TCF-3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of TCF-3 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards TCF-3. \u003cbr\u003e\u003cbr\u003eThe TCF-3 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to investigate the role of TCF-3 in cellular processes, such as gene regulation, development, and differentiation.\u003cbr\u003e\u003cbr\u003eWith its superior specificity, this antibody allows for accurate and precise identification of TCF-3 protein in complex biological systems. Its robust performance ensures reliable and reproducible results, making it an indispensable tool for both basic research and clinical studies.\u003cbr\u003e\u003cbr\u003eThe TCF-3 Polyclonal Antibody is manufactured under stringent quality control measures, guaranteeing batch-to-batch consistency and optimal performance. It is supplied in a convenient format, ready-to-use for immediate application.\u003cbr\u003e\u003cbr\u003eChoose the TCF-3 Polyclonal Antibody for its exceptional specificity, reliability, and versatility, and unlock new insights into the intricate mechanisms governed by TCF-3 protein.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542821978392,"sku":"BT-AP08891","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_665705bd-d87d-4305-8767-3ba5055bf502.png?v=1705639465","url":"https:\/\/danabiosci.com\/products\/new-product-571128","provider":"Dana Bioscience","version":"1.0","type":"link"}