{"product_id":"new-product-570858","title":"Smad1 Polyclonal Antibody","description":"\u003cp\u003eMothers against decapentaplegic homolog 1 encoded by SMAD1 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.\u003c\/p\u003e\n\u003cp\u003eThe Smad1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Smad1 protein expression in various biological samples. This antibody is produced using advanced recombinant technology, ensuring high affinity and specificity towards the target protein.\u003cbr\u003e\u003cbr\u003eThe Smad1 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to accurately quantify and visualize Smad1 protein levels in tissues, cells, and other biological specimens.\u003cbr\u003e\u003cbr\u003eWith its superior sensitivity, this antibody allows for the detection of even low levels of Smad1 protein, making it an ideal choice for studies requiring precise quantification. Its high specificity ensures minimal cross-reactivity with other proteins, guaranteeing reliable and accurate results.\u003cbr\u003e\u003cbr\u003eThe Smad1 Polyclonal Antibody is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming and complex preparation steps. It is available in various sizes to accommodate different experimental requirements.\u003cbr\u003e\u003cbr\u003eIn summary, the Smad1 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of Smad1 protein expression. Its high specificity, sensitivity, and ease of use make it an invaluable asset for researchers in the field of molecular biology, cell biology, and related disciplines.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542764241176,"sku":"BT-AP08375","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f54d824c-d224-46be-9866-0ef1691ecf10.png?v=1705637979","url":"https:\/\/danabiosci.com\/products\/new-product-570858","provider":"Dana Bioscience","version":"1.0","type":"link"}