{"product_id":"new-product-570817","title":"SHIP-1 Polyclonal Antibody","description":"\u003cp\u003eINPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes inositol polyphosphate-5-phosphatase D with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of inositol polyphosphate-5-phosphatase D is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Inositol polyphosphate-5-phosphatase D is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in INPP5D are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants.\u003c\/p\u003e\n\u003cp\u003eThe SHIP-1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of SHIP-1 protein expression in various biological samples. This antibody is produced using state-of-the-art technology and has been rigorously validated to ensure optimal performance and reliability.\u003cbr\u003e\u003cbr\u003eThe SHIP-1 Polyclonal Antibody exhibits exceptional affinity and selectivity towards the SHIP-1 protein, making it an ideal choice for researchers and scientists working in the field of immunology and cell biology. It enables the accurate identification and quantification of SHIP-1 protein levels, facilitating a deeper understanding of its role in cellular processes and disease mechanisms.\u003cbr\u003e\u003cbr\u003eThis antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested and validated in various experimental conditions to ensure consistent and reproducible results. The high specificity of the SHIP-1 Polyclonal Antibody minimizes the risk of cross-reactivity with other proteins, ensuring reliable and accurate data interpretation.\u003cbr\u003e\u003cbr\u003eThe SHIP-1 Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into existing laboratory protocols. It is provided in a liquid formulation, ensuring stability and ease of handling. The antibody is available in different sizes to accommodate various experimental needs.\u003cbr\u003e\u003cbr\u003eIn summary, the SHIP-1 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of SHIP-1 protein expression. Its high specificity, sensitivity, and versatility make it an invaluable asset for researchers seeking to unravel the complexities of cellular signaling pathways and disease mechanisms.\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":47542748741912,"sku":"BT-AP08295","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/BT_Lab_f5e0cd52-ae08-4433-88c6-b97a3272d4c5.png?v=1705637752","url":"https:\/\/danabiosci.com\/products\/new-product-570817","provider":"Dana Bioscience","version":"1.0","type":"link"}